Tri-B Tablets

Indications:

neuropathlea .Trigentinal neuralgia. rheumatic pains .

2.Polyneuriiis, Optic neuritis, Diabetic neuritis, Alcoholic neuritis.

3.NeurItis of pregnancy.

4.Vomiiing of pregnancy.

5.Neuromuscular disorders. Tremors. Cramps.

6Antientia: nutritional inacrocytie anaemia, megaloblastie anaemia of infancy, anaemia of pregnancy. pellagra and following gnIrectolny and in pernicious anaemia

Dosage and administration:  VIP(

Infection: - Ube contents of the ampoules I and 2 are mixed and infected Intramuscularly daily 01 as directed by the physician. Tablets:- 1^.2 tablets daily or as directed by the physician.

Contraindications:

I•Not used to trial meg:fluidal/Me anaemia of pregnancy.

2-Patients with known sensitivity to any of the components.

Side effects: Parenteral administration of thiamine hydrochloride solutions may cause allergic reactions.

Drug Interaction:

·   Colchicine may interfere with n itatitin 112 absorption leading to megaloblastic anaemia.

- Reduced absorption of vitamin It was observed in case of patients receiving 'min^.:dont citrate or calcium gluconate with metformln. - Biochemical interactions occur between pyridoxal phosphate and certain drugs as Isoniarid (Increase urinary excretion of ‘111101i0   Penicillamine (prolonged use), cycloscrine and /is dralacine .

- Vitamin 86 enhances peripheral decarbonc)lation of les odopa :Ind reduces its effectiveness thus maul be avoided in patients necking Ins odopa

·   the effect of folic acid may he diminished In patients receiving barbiturates, and co- trImosazole.

·   Folic acid should not be given to patients using Ando,nns itisants us netts loin. phenobarbitone or primodone since it reduces their blood levels.

-Sulphasalazine can intpair the absorption of folic acid in the gut.

Pregnancy and lactation:

·   Ind II^-dearly needed in pregnancy.

·   Vitamin B complex excreted in breast milk. sin caution should be taken during lactation.' Precautions and warnings: Serious hypersensith By reactions may occur. Package and storage:

vei•r,mr.• Box of 6 double

ampoules.

Box of 2 strips s        tablets.

Cade N0.

2^.'20D9

Box of 3 double ampoules.

rob.

-Store Inn dry place away from light.

-Store In a temperature below 2.5°C.                                                                                                6 Amu. 351239

Instructions to patients:

Keep out of reach of children.

Manufactured by The NILE Co. for Pharmaceuticals and Chemical Industries - Cairo - A.R.E. R.C.C. 115668