Indications:
CURISAFE is indicated in the treatment of infections caused by Cefadroxil-susceptible strains of Gram-positive Pathogens including .lactamase and non -laclomase Producing Staphylococcl -hemolytic streptococci.Streplococcus pneumonia," and Streptococcus pyogenes. It Is also effective against several Gram-negative bacteria as follows-. • Infections of the Respiratory Tract, sinusitis otitis media tonsillitis pharyngitis laryngitis bronchitis bronchopneumonia bronchiectasis pulmonary abscess empyema and pleurisy
infections of the Skin and Soft tissues
infected traumatic and posteperative wounds.
• Infections of the Urfnery Tract: pyalonephrills, cystitis, urethritis.
• Infections of the Genital Tract In Adults : prostatitis . orchitis, epididymo orehitis, adnexities endometritis and other genital infections
• Miscellaneous Infections: osteomyelitis. septic arthritis, intra-abdominal Infections and dental infections.
DOSAGE AND ADMINISTRATION:
Curisafe is acid stable and may be administered orally regard to meals. administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with Oral Cephalosporin therapy.
ADULTS: Urinary Tract Infection: for uncomplicated lower urinary tract infection (i.e..cystitis) the usual dosage is 1 or 29 per day in single dose or two equally divided doses. For all other urinary tract infection the usual dosage is 2 g per day in two equally divided doses. Skin and skin structure infections: for skin and skin structure infections the usual dosage is 1 g per day in a single dose or two equally divided doses. Pharyngitis and Tonsillitis: due to group A beta-hemolytic streptococcal pharyngitis and tone/141s - 1 g per day In or a single dose two equally divided i doses for at least ten days upper and lower respiratory tract Infections: for mild infections the usual dosage is 1 g per day in two equally divided doses. Moderato to saver infections the recommended dosage is 1 g to 29 daily in two equally divided doses. Children: the recommended dosage for children is 25 to 50 mg/kg/day in two equally divided doses (every 12 hours) as indicated. For pharyngitis, tonsillitis and impetigo the recommended daily dosage my be administrated as single dose or in boo equally divided doses (every 12 hours)
Side Effects: CURISAFE is safe and well-tolerated. CURISAFE might cause GI disturbances including nausea, abdominal cramps and diarrhea. Less common side effects include urticaria, skin rash. angioneurotic edema and transient leucopenia.
Pregnancy and Lactation :
Preparations containing cephaiesporins are used during pregnancy and lactation only if clearly indicated