Indications:
• Acute constipation.
• Chronic constipation and bowel training: extremely effective in the management of chronic constipation, particularly in order patients. By gradually lengthening the interval between doses as colonic tone improves, the drug is effective in redeveloping proper, bowel hygiene. there is no tendency to rebound and prolonged use does not cause habit formation.
Preparation for radiography, sigmoidoscopy, proctoscopy or ultrasonography: excellent in eliminating fecal and gas shadows. for unscheduled endoscopic examinations,adequate preparation is usually obtained with a single suppository.
• Pre-operative preparation: an ideal laxative for emptying the gastrointestinal tract.
• Post — operative and postpartum care: A suppository can be given to replace an enema. Tablets are given as an oral laxative to restore normal bowel hygiene after surgery or delivery , with no contraindications to nursing mothers. I reparation for delivery: Suppositories can be used to replace enemas in the first stage of labor provided that MIMI they are given at least two hours before onset of the second stage.
Dosage:
• Enteric coated tablets:
tablets must be swallowed whole, not chewed or crushed, on a hill or empty stomach and should not be taken within one hour of taking antacids.
— Adults:
Two tablets at bedtime usually suffice for an ordinary laxative effect, This results in one or two soft formed stools the next morning. When taken before breakfast , they produce an effect within 6 hours. two to four tablets are usually needed, but up to six tablets may he safely given, in preparation for special procedures when greater assurance of complete evacuation of the colon is desired. Higher doses may result in several loose unformed Stools.
— Children:
4 years old and over: One tablet.
• Suppositories:
Adults: to obtain a bowel movement at a short notice or to replace an enema, one 10 mg suppository is Used and it is usually " effective in 1540 minutes.
_ Children:
One 5 mg suppository is used