Pregnancy & lactation
When antibiotic therapy is required during pregnancy, Amoxycillin may be considered appropriate, as it has show no teratogenic effects. - It may be given during lactation with taking in mind that trace quantities can be detected in breast milk.
Posology and method of administration :
Adults .
- Mild infections : 250 mg every 8 hours .
- Moderate to severe infections : 500 mg every 8 hours.
- Very severe infections :1000 mg every 8 hours .
Children up to 10 years :
- 125 to 250 mg every 8 hours .
- Under 20 kg body-weight : - 20 to 40 mg / kg daily in 3 divided doses,
Overdosage:
In case of overdosage G.I.T effects may occur such as nausea, vomiting & diarrhea Amoxycillin may be removed from circulation by haemodialysis.
Method of reconstitution :
To reconstitute the dry powder for suspension : Add water to the bottle in 2 portions to the mark & shake well after each addition. The reconstituted formulation is stable for 7 days - Shake well before use. _ To reconstitute the vial : - - - For IM injection, the powder is dissolved in 2-3 ml of water for injection. - For IV injection, the powder is dissolved in 5-10 ml of water for injection. - Reconstituted solutions for IV or IM should be used immediately or within 2 hours if kept at room temperature or within 24 hours if kept at SC.
Storage :
- Keep at temperature not exceeding 30C. - Keep out of reach of children
Presentation :
Box of 8,12,16,20,100,500 ,1000 capsules. Bottle of powder for oral susp. 80,100 ml. Box of one vial. Box of 50 vials