Clindam

Clindam

Capsules

Composition:

Each capsule contains: Clindamycin Hydrochloride equivalent to 150 mg or 300 mg Clindamycin.

 Properties:

Clindarnycin in-vitro activity covers the following organisms: Gram-Positive: Aerobic organisms: Staphylococcus aureus, Staphylococcus epidermis (both penicillinase and non-penicillinase producing strains), Streptococci (except S.faecalis), pneumococci. Anaerobic organisms: Non spore forming Bacilli such as Propionibacterium species. Gram-Negative: Anaerobic Bacilli such as Bacteroides species and Fusobacterium species.

 Indications:

 Infections with microorganisms susceptible to Clindamycin such as:

 - Respiratory tract infections.

 - Skin and soft tissue infections.

- Dental infections.

- Genital and post-surgical infections

. Contraindications:

Clindamycin demonstrates cross resistance with Lincomycin. Some Staphylococcus strains originally resistant to Erythromycin rapidly develop resistance to Clindamycin. Clindam is constrained in patients with history of hypersensitivity to Clindamycin or Lincomycin.

 Usage in pregnancy:

 Safety for use during pregnancy has not been established.

 Side Effects:

 Gastrointestinal disturbances: abdominal pain, nausea, vomiting and diarrhoea may occur.

Dosage:

 Mild to moderately severe infections: 150 to 300 mg every 6 hours. Severe infections: 300 to 450 mg every 6 hours.

 Presentation:

 Clindam 150 mg capsules: A box containing 2 blisters, each of 8 capsules. Clindam 300 mg capsules: A box containing 1 blister of 8 capsules. A box containing 2 blisters, each of 8 capsules.

 

CIPROCIN

For The Medical Profession Only

CIPROCIN

Film-Coated Tablets - Vials (IV) Broad - Spectrum Fluoroquinolone Antibacterial

Indications:

 -Treatment of infections due to susceptible micro-organisms:

 -Urinary tract infections.

 -Acute sinusitis, and malignant otitis externa.

-Lower respiratory tract infections.

 -Exacerbations of cystic fibrosis.

 -Bone and joint infections.

 -Skin and soft tissue infections.

 -Gastrointestinal tract infections including biliary tract infections, infectious diarrhea, typhoid and paratyphoid fevers.

 -Genital tract infections: prostatitis, gonorrhea and chancroid.

-Septicemia and peritonitis.

-Surgical infection prophylaxis.

 -Meningococcal meningitis prophylaxis.

 -Infections in immunocompromised patients (neutropenia).

 -Inhalation anthrax.

 Dosage and Administration:

Oral Route Clprocinn can be taken without regard to meals. CiprocIn8 Tablets should be given every 12 hours.

Properties:

 CiprocIn0 is one of the most potent of the fluoroquinolone antibacterial group. It is bactericidal acting by inhibition of the A subunit of DNA gyrase enzyme essential for bacterial DNA reproduction. Clprocin® has a broad spectrum of activity against most Gram-negative bacteria and many Gram-positive bacteria including Enterobacteriaceae. including E. coli. Proteus, Klebsiella, Salmonella, Shigella. Serratia, Citrobacter. Enterobacter, Providentia, Yersinia; Pseudomonas aeruginosa: Moraxella catarrhalis and Haemophilus inlluenzae (including beta-lactamase producing strains). Haemophilus parainfluenzae and ducreyi, Neisseria gnonorrhoeae (including beta-lactamase producing strains), Neisseria meningitidis. Campylobacter app., and Vibrio spp.; Staphylococci (including penicillinase-producing and penicillinase-nonproducing strains and some methicillin-resistant strains). Streptococci (including pyogenes, faecalis and

pneumoniae). Clprocin® has some activity against mycobacteria, and mycoplasmas.

Pharmacokinetics:

 Ciprofloxacin is rapidly and well absorbed from the gastrointestinal tract. Oral bioavailability is about 70% and a peak plasma concentration is achieved 1 - 2 hours after a dose of 500 mg by mouth. Absorption may be delayed by the presence of food but is not substantially affected overall. Plasma half-life is about 3.5 - 4.5 hours. Protein binding ranges from 20 - 40%. Ills widely distributed in the body and tissue penetration is generally good. High concentrations are achieved in bile. Ciprofloxacin is eliminated primarily by urinary excretion, but non-renal clearance may account for about a third of elimination and includes hepatic metabolism, biliary excretion and possible transluminal secretion across the intestinal mucosa. About 40 - 50% of the oral dose is excreted unchanged in urine and about 15% as metabolites which have antimicrobial activity, but are less active than unchanged ciprofloxacin. Up to 70% of the parenteral dose may be excreted unchanged and within 24 hours and 10% as metabolites. Fecal excretion over 5 days has accounted for 20- 30% of an oral dose and 15% of an intravenous dose.

 

Alexoprine

Indications & Usage :

mild to moderate pain pyrexia antiplatelet relief of all symptoms associated with common cold and influenza such as headache, pain and fever. • Antipyretic in febrile conditions including rheumatic fever. • Analgesic for pain of different etiologies as headache, toothache, migraine and rheumatic pain. • ills suitable for patients who suffer from hyperacidity or gastric ulcers and can not receive normal aspirin therapy. It can also be used for long term therapy without causing irritation or ulceration to gastric mucosa

Side effects :

Generally mild and infrequent but high incidence of gastrointestinal Irritation with slight asymptomatic blood loss, increased bleeding time, bronchospasm and skin reactions in hypersensitive patients

Warnings & Precautions :

 Asthma, allergic disease, impaired renal or hepatic function (avoid if severe), dehydration, pregnancy, elderly.

 Dosage & Administration :

 As directed by the physician or as follows. Children for 12 years '2 -3 Alexoprine 75 mg tablets 2 - 3 times daily after meals. Adults : 1 - 2 Alexoprine Forte tablets 3 times daily after meals. It is preferable to disintegrate the tablets in some water, stir and then drink

جاست ريج Gast reg

لعلاج إضطرابات الجهاز الهضمى والقولون ومضاد للتقلصات
gastrointestinal ,motility ,regulator

سعر العلبة 18جنيهاً

دواعى الإستعمال

القولون العصبى
حالات الإمساك المزمن
إضطرابات الهضم الوظيفية المصحوبة بآلام وتقلصات البطن
الإمتلاء
الإنتفاخ
الإمساك او الإسهال
بعد العمليات الجراحية لسرعة إستعادة حركية الجهاز الهضمى الطبيعية

موانع الإستعمال

الحساسية المفرطة للمادة الفعالة

الجرعة

الأقراص 100مج1-2قرص ثلاث مرات يومياً
الأقراص200مج قرص 3مرات يومياً
الشراب
الأطفال حتى 6 شهور 1\2 نصف معلقة صغيرة 2-3مرات يومياً
6شهور الى سنة ملعقة صغيرة مرتين يومياً
سنة الى 5سنوات ملعقة صغيرة 3مرات يومياً
أكثر من خمس سنوات 2 ملعقة صغيرة 10ملليلتر 3مرات
الحقن
الجرعة العادية فى البالغين50-100مج 1-2 أمبول فى اليوم
لاتزيد الجرعة اليومية عن طريق الحقن العضلى او الوريدى عن 400مجم فى الحالات الحادة

الأقماع
2-1 قمع يومياً

كليندام 300 Clindam 300

سعر العلبة 21 جنية

دواعى الاستعمال

الأصابة بالميكروبات الحساسة لكلينداميسين مثل

1-عدوى الجهاز التنفسى

2-عدوى الجلد والأنسجة الرخوة ,

3-عدوى الاسنان

4-عدوى الجهاز التناسلى وما بعد الجراحة

موانع الاستعمال

1-لا يستخدم فى المرضى المصابين بالحساسية لكلينداميسين او لينكوميسين

2-أثناء الحمل لم يثبت الآمان فى استخدامه خلال فترة الحمل

الجرعة

حالات العدوى الخفيفة والمتوسطة 50/300 كل 6 ساعات

حالات العدوى الشديدة 300/450 كل 6 ساعات