CURISAFE

Indications:

 CURISAFE is indicated in the treatment of infections caused by Cefadroxil-susceptible strains of Gram-positive Pathogens including .lactamase and non -laclomase Producing Staphylococcl  -hemolytic streptococci.Streplococcus pneumonia," and Streptococcus pyogenes. It Is also effective against several Gram-negative bacteria as follows-. • Infections of the Respiratory Tract, sinusitis  otitis media  tonsillitis pharyngitis  laryngitis bronchitis bronchopneumonia bronchiectasis pulmonary abscess empyema and pleurisy

 infections of the Skin and Soft tissues

infected traumatic and posteperative wounds.

 • Infections of the Urfnery Tract: pyalonephrills, cystitis, urethritis.

• Infections of the Genital Tract In Adults : prostatitis . orchitis, epididymo orehitis, adnexities endometritis and other genital infections

• Miscellaneous Infections: osteomyelitis. septic arthritis, intra-abdominal Infections and dental infections.

DOSAGE AND ADMINISTRATION:

Curisafe is acid stable and may be administered orally regard to meals. administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with Oral Cephalosporin therapy.

 ADULTS: Urinary Tract Infection: for uncomplicated lower urinary tract infection (i.e..cystitis) the usual dosage is 1 or 29 per day in single dose or two equally divided doses. For all other urinary  tract infection the usual dosage is 2 g per day in two equally divided doses. Skin and skin structure infections: for skin and skin structure infections the usual dosage is 1 g per day in a single dose or two equally divided doses. Pharyngitis and Tonsillitis: due to group A beta-hemolytic streptococcal pharyngitis and tone/141s - 1 g per day In or a single dose two equally divided i doses for at least ten days upper and lower respiratory tract Infections: for mild infections the usual dosage is 1 g per day in two equally divided doses. Moderato to saver infections the recommended dosage is 1 g to 29 daily in two equally divided doses. Children: the recommended dosage for children is 25 to 50 mg/kg/day in two equally divided doses (every 12 hours) as indicated. For pharyngitis, tonsillitis and impetigo the recommended daily dosage my be administrated as single dose or in boo equally divided doses (every 12 hours)

Side Effects: CURISAFE is safe and well-tolerated. CURISAFE might cause GI disturbances including nausea, abdominal cramps and diarrhea. Less common side effects include urticaria, skin rash. angioneurotic edema and transient leucopenia.

Pregnancy and Lactation :

 Preparations containing cephaiesporins are used during pregnancy and lactation only if clearly indicated

Combifloxin

Indications:

Combifloxin is indicated in the treatment of a wide range of infections such as:

I-Respiratory Tract infections:

 - Bronchitis - Pneumonia – Emphysema

 2- Ear, Nose and Throat infection:-

  Otitis Media - Sinusitis - Tonsillitis - Pharyngitis

3- Gastro- Intestinal Tract Infections:

 - Enteritis - Typhoid & Paratyphoid fever - Cholecystitis –

 4-titirto genital Tract Infections

 - Cystitis - Pyelonephritis - Prostatitis -Gonorrhea

5- Skin and Soft- Tissue Infections:

-Boils -Abscesses -Carbuncles - Cellulitis -Post-Operative wound infections - Intra abdominal sepsis

6-Bone infections:

-Osteomyelitis -Septic arthritis

7-Other infections:

-Septicaemia -Endocarditis -Peritonitis - Billiary tract infections

Dosage Administration:

 Adults: 250-1000 mg every6-8 hours

Contraindications:

 Patients with known hypersensitivity to penicillin

Side effects:

 As with other penicillin, side effects are usually mild and transient and they are limited to diarrhea, indigestion and skin rashes.

Precautions:

 In patients with sever renal impairment, dose should be reduced

Packing:

 A Box of 8 tablets in a blister

CIPROFAR

Indications

Ciprofar is indicated for treatment of infections caused by ciprofloxacin-susceptible organisms:

 • Urinary tract Infections :

 pyelonephritis, cystitis and urethritis including complicated and uncomplicated conditions.

 • Genital tract infections :

 prostatitis, epididymilis. epididymo-orchitis, salpingibs and Salcingo-oophoritis.

• venereal diseases :

 urethral and cervical gonorrhea. nongonococcal urethritis and chancroio.

• Gastrointestinal tract infections :

infectious diarrhea, enteritis, enter000litis and enteric ( typhoid and paratyphoid ) fevers.

• Biliary tract infections :

 cholecystitis, cholangilis and chcledochitis

Calcium

Dosage:

Adults 1 - 2 sachets daily.

Children 1/2 – 1 sachet daily (-before or-during-meals ).

 Dissolve the content of the sachet in half glass of water to get a palatable effervescent solution & drink immediately

Indications:

 - During childhood, pregnancy & lactation to overcome the increased demand for calcium.

-osteomalacia , rickets, post-menopausal & senile osteoporosis.

- Cases of excessive loss or reduced absorption of calcium such as in prolonged treatment with corticosteroids, in cases of gastrectomy & in hypoparathyroidism.

 - Renal osteodystrophy.

 - Chronic renal failure

Side effects: Minor gastrointestinal disturbance rarely occurs

Contraindications:

 Hypercalcaemia, hypercalciuria , calcium renal calculi

Calcimate

Indications & Usage :

 • Calcimate capsule are used as a calcium supplement in hypocalcemia states e.g. pregnancy, lactation

Calcimate Capsule are used as supplement to reduce the risk  of osteoporosis  

• In eldery  specially women which tend to have fragile bone in later  ages

-Used as supplement dining teenagers and early adults to build  and  maintain good bone health

Contra — Indications

• Renal impairment.

 • Hypercalcemia and hypercalciuria.

 • Gastric and duaderal ulcers

Side — Effects :

-                                          Sometimes constipation may occur with high calcium carbonate intake.

-                                          - Hypercalcemia.

-                                          • Mild gastrointestinal disturbance.

-                                          - arrhythmias

Dosage & Administration

One capsule daily with meals or according to physician  instructions.

- This dietary requirement varies with age and is relatively greater in pregnancy and lactation . adequate calcium intake is important but daily intake above 2000 mg calcium are not likely to provide any additional benefit.