Acetylcistein

Indications:

- Disorders of the respiratory tract associated with excessive viscous

mucous such as in bronchitis, pneumonia, asthma, bronchiectasis,

Side effects:

Nausea, vomiting, heart burn and diarrhea have been rarely reported.  Precautions:

Acetylcysteine must be used with caution in patients with history of peptic ulceration and avoided in patients with active ulcer.

- Caution should be taken in patients who complain from hypertension, heart failure, renal diseases, oedema and all cases that need salt restriction.

AMPIFLUX

(Capsules and Powder for Oral Suspension

Broad Spectrum Antibiotic Combination

Indications

Composition : Each 250 mg capsule contains: Ampicillin (as trihydrate) equivalent to 125 mg Ampicillin activity Flucloxacillin (as sodium salt) equivalent to 125 mg Flucloxacillin activity Each 500 mg capsule contains : Ampicillin (as trihydrate) equivalent to 250 mg Ampicillin activity Flucloxacillin (as sodium salt) equivalent to 250 mg Flucloxacillin activity Each 5 ml of oral suspension contains Ampicillin ( as trihydrate ) equivalent to 125 mg Ampicillin activity Flucloxacillin ( as magnesium salt ) equivalent to 125 mg Flucloxacillin activity Properties AMP1FLUX is a broad spectrum antibiotic combination of ampicillin and flucloxacillin acting synergistically woVna n e of ani Ampicillin is a broad spectruM  profile. Ampicillin possesses a potent bactericidal action against a wide range of Gram-positive and Gram-negative non-penicillinase-producing bacteria. Flucloxacillin is a bactericidal with a broad spectrum activity against many strains of 11-lactamase-producing- bacteria, particularly li-lactamase-producing Staphylococci. Flucloxacillin is also active against Gram-positive aerobic and anaerobic bacilli. AMPIFLUX inhibits the transpeptidases responsible for the synthesis of peptidoglycan, the essential structure component of bacterial cell wall. This leads to complete eradication of susceptible organisms. Compared to ampicillin alone, the antibacterial spectrum of AMPIFLUX (ampicillin and flucloxacillin) covers a wider range of Gram-positive and Gram-negative it-lactamase and non-(t-lactamase-producing bacteria. AMPIFLUX has a high dinicaLefficapy_in_treatment_ of_mixad infez,tiOns_ancLinfections_caused by -tains

bacterial strains resistant to most penicillins and cephalosporins. AMPIFLUX is safe and well tolerated and is formulated as capsules and suspension to suit different age groups (adults, children and infants). Pharmacokinetics AMPIFLUX is stable in gastric medium and is well absorbed from the GIT. The dose should preferably be taken at least 30 minutes before meals as absorption is affected by the presence of food. Peak plasma concentrations are achieved within 1-2 hours. Plasma protein binding is about 20% for ampicillin and 95% for flucloxacillin. Both ingredients of AMPIFLUX are well distributed into most body tissues and fluids including liver, lungs, heart, kidneys, prostate, skin, mucous membranes, bone and ascitic, pleural, synovial and ocular fluids. They also penetrate middle ear effusions. maxillary sinus, bronchial secretion and sputum. There is little diffusion into the CSF except when meninges are inflamed. AMPIFLUX is metabolized to a limited extent and 20 - 40% of ampicillin and about 50% of flucloxacillin are excreted in the urine and only small amounts are excreted in the bile. Plasma half-life is 1-2 hours for ampicillin and about 1 hour for flucloxacillin. AMPIFLUX crosses the placenta and appears in breast milk. Hemodialysis removes ampicillin, but not flucloxacillin, from the body. Antimicrobial Spectrum AMPIFLUX possesses a potent bactericidal acitivity against a wide range of pathogenic microorganisms including 13-lactamase-producing strains: Gram-positive bacteria Staphylococci including Staph. aureus, Streptococcus pneumoniae, S. pyogenes, S. faecalis, S. viridans. Bacillus anthracis and Listeria monocytogenes. Gram-negative bacteria Haemophilus influenzae, Neisseria gonorrhoeae, N. meningitidis, Proteus mirabilis, Escherichia coli and Salmonella and Shigella species. Anaerobes : Clostridium species, Peptococcus species and Bacteroids species including B. fragilis.

Ampicillin

Indications

 Amplcillin is a bactericidal which has a broad spectrum of activity against the following microorganisms

- Gram Negative microorganisms such as shigella, salmonella, E. coli, H. influenzae P. mirabilis, and 8 pertussis and Gram Negative cocci such as B Catarrhalis .Neisseria gonorrhea and N. meningitides

 - Gram Positive organisms such as streptococci. pneumococci and non penicillinase-producing staphylococci - it can be used for treatment of infections of the following systems :Respiratory tract, 3.1 tract and the urinary system also meningitis and septicemia

Side Effects :

- Allergic reactions occur in sensitized persons

- Skin rashes - The erythematous maculopapular eruptions are characteristic of Ampicillin and often appear more than and 7 days after commencing treatment

Store in a temperature not exceeding 25 °C. - Keep in dry place ,protect from light.

Avipect

Side effects

There may be occasional cases of drowsiness, gastrointestinal upset, dryness of the mouth, urinary retention, palpitations and hypersensitivity reactions during treatment with the recommended doses. After higher doses, hallucinations, restlessness and disorientation, and in small children agitation, may occasionally be seen. Blood dyscrasias, which very rarely occur with antihistaminics, have not been observed so far with pheniramine maleate preparations. In patients with narrow angle glaucoma,an increase in intraocular pressure is possible: therelore, treatment of such patients with Avipect syrup must be carried out under ophthalmological supervision.

Dosage and administration

Adults: 1 1/2 - 2 teaspoonfuls, 2-3 times daily, unless otherwise prescribed by the doctor. Children aged 4 months - 1 year: 1/2 teaspoonful, 2 - 3 times daily,unless otherwise prescribed by the doctor.

Children aged 1-5 year: 1/2 - 1 teaspoonful, 2 - 3 times daily unless otherwise prescribed by the doctor

The dose should not exceed 3 mg pheniramine maleate /kg body weight per day.

Avipect syrup shold not be taken on an empty stomach.

Special notes

Even at the dosages prescribed, systemic use of this preparation may affect the patient's alertness to such an extent that the ability to drive or operate machinery is impaired, particularly if the drug is taken in combination with alcohol. The dosage and time of ingestion should be adjusted according to the patient's activities.

Interactions

The effect of drugs which act on the central nervous system, such as tranquillizers, neuroleptic agents, MAO inhibitors and sedatives, and of alcohol may be potentiated.

Storage

Store below 30 °C

Expiry date

Do not use later than the date of expiry.

Alveolin-P

Indications:

·   Food supplement to Improve respiratory functions.

Dosage & Administration:

Unless otherwise prescribed,

·   Adults: 1-2 Tablespoonful 3 times daily.
·   Children: 1/2-1 Teaspoonful 2-3 times daily.
Shake well before use.

Side effects:

Alveolin-P syrup is a safe natural product without reported side effects.

Contraindications:

Alveolin-P syrup Is a safe natural product without reported contraindications.

Package:

Alveolin-P syrup: bottle of 100 ml.

Storage:

Store away from light and below 30°C. Keep out of reach of children.