indications and dosage
1 - Duodenal and benign gastric ulcers:
Treatment : Oral 150 mg twice daily or soc at bedtime tor at least 4-6 weeks.
Maintenance : Oral 150 mg at bedtime tor more than year it required.
- Gastro - oesophageai reflux :
Treatment : Oral 150 mg twice daily for not more than 6 weeks.
- Gastric hypersecretory conditions :( e.g. Zollinger - Ellison syndrome, systemic rnastocytosis.
multiple endocrine adenomas ). ‘
-Upper gastrointestinal stress-induced ulceration and bleeding :
Treatment and Prophylaxis : Oral 150 mg twice daily, or parenteral therapy may be used.
- Aspiration syndrome : -
Prophylaxis : Oral 150 mg may be given 2 hours before the induction oi anaesthesia or at the start of labour to reduce the danger oi aspiration of acidic gastric contents and may be repeated_ at intervals of 6 hours if required
side effects/ Aderse effects
' “headache rare hypersensitivity reactions bradycardia, dizziness, skin rash. transient revereible
' changes in liver functlon teats may occur.
Reversible leuoopserria‘ and tlirombooytopaentt-‘fhave been
Unlike cimeticiihe, Ranitldlne has little or no anti-androgenic etiect and lncldenceot
gynaecothastia and impotence in patients treated with closes oi Ranitidine has been
reported not to differ from that encountered in the general population.
Precautions :
. The usual dosage should be reduced tor patients with liver impairment. .- it is generally considered that drug interaction is far less in comparison to cimetidine.
- Gastric malignancy must be excluded before therapy with Ranltak.
- Ranitak should only be used during pregnancy and nursing mothers if clearly needed.
keep out oi reach oi children.
Ranitak 150 mg : Box oi 20 tablets or 1000 tablets . _ Q
Ranitak 300 mg Box of 20 tablets.
Produced by ct.
SEDICO Pharmaceutical Co.
6 October City - Egypt